Dr. Dvora Sradni

Dr.
Dr. Dvora Sradni
Telephone: 
Office: 

CV

 

Place and Date of Birth:  Israel, January, 25, 1948.

 

Marital Status:  Married + 3.

 

Education:

           

1966-1970               B.Sc. Dept. of Life Science, Bar-Ilan University, Ramat-Gan.

 

1970-1972               M.Sc. Dept. of Life Science, Bar-Ilan University, Ramat-Gan.

 

1973-1981               Ph.D. Dept. of Life Science, Bar-Ilan University,  Ramat-Gan.

 

 

 

Brief Chronology of Employment:

 

1970-1972               Teaching Assistant, Dept. of Life Science, Bar-Ilan University.

 

1973-1979               Instructor, Dept. of Life Science, Bar-Ilan University.

 

1979-1981               Guest Worker, St. Elizabeth Hospital (NIH), Washington D.C.

 

1981-1985               Researcher, National Virology Lab. Shiba Medical Center, Ramat-Gan, Israel.

 

1985-1987               Guest Researcher, NINCDS, IDB, IRP, National Institute of Health, Bethesda, MD.

 

1987-1991               Researcher, Cellular Immunology Lab. Meir Hospital, Kfar-Saba.

 

1991-1992               Instructor, Interdisciplinary Dept. Bar-Ilan University, Ramat-Gan.

 

1992-1999               Lecturer, Interdisciplinary Dept. Bar-Ilan University, Ramat-Gan.

 

  1. Deputy head of the Interdisciplinary Dept. Bar-ilan university, Ramt-Gan.

 

1999-present           Senior Lecture, Interdisciplinary Dept. Bar-Ilan University, Ramat-Gan.

 

2011-present           Head of the Interdisciplinary Dept. Bar-ilan university, Ramt-Gan.

Publications

Sredni-Kenigsbuch, Devorah "Stress, Immunology, and Cytokines" Int J Neurosci, In Press.

 

-----------------

Sredni-Kenigsbuch, Devorah, Shohat, M., Shohat, B., Ben Amitai, D., Chan, CC, David, M.. "The novel tellurium immunomodulator AS101 inhibits interleukin- 10 production and p38 MAPK expression in atopic dermatitis" J Dermatol Sci., vol. 50, 2008, pp. 232-235.

 

-----------------

Sredni, Benjamin, Geffen-Aricha, R, Duan, W, Albeck, Michael, Shalit, F, Lander, HM, Kinor, N, Sagi, O, Albeck, Amnon, Yosef, S, Brodsky, M, Sredni-Kenigsbuch, Devorah, Sonino, T, Longo, DL, Mattson, MP, Yadid, Gal. "Multifunctional tellurium molecule protects and restores dopaminergic neurons in Parkinson's disease models" FASEB Journal, vol. 21, 2007, pp. 1870-1883.

 

-----------------

Shohat, M, Mimouni, D, Ben Amitai, D, Sredni, Benjamin, Sredni-Kenigsbuch, Devorah, Shohat, B, David, M. "In vitro cytokine profile in childhood alopecia areata and the immunomodulatory effects of AS-101 " Clin. Exp. Dermatol. , vol. 30, 2005, pp. 432-434.

 

-----------------

Armony- Sivan, R., Eidelman, AI., Lanir, A., Sredni-Kenigsbuch, Devorah, Yehuda, Shlomo. "Iron status and neurobehavioral development of premature infants" J Perinatol, vol. 24, 2004, pp. 757-762.

 

-----------------

Sredni-Kenigsbuch, D. "Th1/Th2 Cytokines in the Central Nervous System" International Journal of Neuroscience, vol. 112, 2002, pp. 665-703.

 

-----------------

Shohat, M., Hodak, E., Sredni, Benjamin, Shohat, B., Sredni-Kenigsbuch, Devorah, David, M.. "Cytokine profile of patients with mycosis fungoides and the immunomodulatory effect of AS101" Acta Derm Venereol, vol. 81, 2001, pp. 255-257.

 

-----------------

Xu, R.H.; Peng, Y.; Fan, J.; Yan, D.H.; Yamagoe, S.; Princler, G.; Sredni-Kenigsbuch, D.; Ozato, K. and Kung, H.F. "Histone Acetylation is a Checkpoint in FGF Stimulated Mesoderm Induction" Develop. Dynam., vol. 218, 2000, pp. 628-635.

 

-----------------

Sredni-Kenigsbuch, D.; Kambayashi, T. and Strassmann, G. "Neutrophils Augment the Release of TNF Alpha from LPS-Stimulated Macrophages Via Hydrogen Peroxide" Immunol. Lett., vol. 71, 2000, pp. 97-102.

 

-----------------

Xu, R.H.; Ault, K.T.; Kim, J.; Park, M.J.; Hwang, Y.S.; Peng, Y.; Sredni-Kenigsbuch, D. and Kung, H.F. "Opposite Effects of FGF and BMP-4 on Embryonic Blood Formation: Roles of PV.1 and GATA-2" Developmental Biology, vol. 208, 1999, pp. 352-361.

 

-----------------

Xu, R.H.; Lechleider, R.J.; Shih, H.M.; Hao, C.F.; Sredni-Kenigsbuch, D.; Roberts, A. and Hung, H.F. "Functional Analysis of Human Smad1: Role of the Amino-Terminal Domain" Biochemical and Biophysical Research Communications, vol. 258, 1999, pp. 366-373.

 

-----------------

Sredni-Kenigsbuch, D. "Cytokines Pattern in Chronic Fatigue Syndrome" In: Yehuda and Mostofsky (eds.) Chronic Fatigue Syndrome, pp. 131-159. New York, Plenum Press, 1997.

 

-----------------

Strassman, G.; Kambayashi, T.; Jacob, C.O. and Sredni-Kenigsbuch, D. "The Immunomodulator AS-101 Inhibits IL-10 Release and Augment TNF and IL-1 alpha release by Mouse and Human mononuclear Phagocytes " Cellular Immunol. , vol. 176, 1997, pp. 180-185.

 

-----------------

Xu, R.H.; Kim, J.; Taira, M.; Sredni-Kenigsbuch, D. and Kung, H. "Studies on the Role of Fibroblast Growth Factor Signaling in Neurogenesis Using Conjugated/Aged Animal Caps and Dorsal Ectoderm-Grafted Embryos" J. Neuroscience, vol. 17, 1997, pp. 6892-6898.

 

-----------------

Xu, R.H., Kim, J., Taira, M., Lin, J.J., Zhang, C., Sredni-Kenigsbuch, Devorah, Evans, T., Kung, H.. "Differential Regulation of Neurogenesis by the Two Xenopus GATA-1 Gens" Mol. Cell. Biol., vol. 17, 1997, pp. 436-443.

 

-----------------

Xu, R.H., Dong, Z., Maeno, M., Kim, J., Suzuki, A., Ueno, N., Sredni-Kenigsbuch, Devorah, Colburn, N.H., Kung, H.. "Involvement of Ras/Raf/ AP-1 in BMP-4 Signaling During Xenopus Embryonic Development " Proc. Natl. Acad. Sci. , vol. 93, 1996, pp. 834-838.

 

-----------------

Enk, C.D.; Sredni-Kenigsbuch, D.; Blauvelt, A. and Katz, S.I. "Induction of IL-10 Gene Expression in Human Keratinocytes by UVB Exposure in Vivo and in Vitro" J. Immunol., vol. 154, 1995, pp. 4851-4856.

 

-----------------

Xu, R.H.; Kim, J.; Taira, M.; Zhan, S.; Sredni-Kenigsbuch, D. and Kung, H. "A Dominant Negative Bone Morphogenetic Protein 4 Receptor Causes Neutralization in Xenopus Ectoderm" Biochem. Biophys. Res. Comm., vol. 212, 1995, pp. 212-219.

 

-----------------

Dastgheib, K., Hikita, N., Sredni, Benjamin, Albeck, Michael, Sredni-Kenigsbuch, Devorah, Nussenblatt, R.B., Chan, C.. "Ocular Inflamation Stimulated by the Immunomodulator AS101 [ammonium Trichloro (dioxyethelene Tellurate)] " Current Eye Res. , vol. 13, 1994, pp. 603-610.

 

-----------------

Mekori, Y.A.; Baram, D.; Goldberg, A.; Hershkoviz, R.; Reshef, T. and Sredni-Kenigsbuch, D. "Nedocromil Sodium Inhibits T Cell Function in Vitro and in Vivo" J. Allergy and Clin. Immunol., vol. 91, 1993, pp. 817-824.

 

-----------------

Fishman, P.; Kamashta, M.; Ehrenfeld, M.; Vianna, J.; Hughes, G.R.; Sredni-Kenigsbuch, D.; Zigelman, R.; Sabo, G. and Shoenfeld, Y. "Interleukin-3 Immunoassay in Systematic Lupus Erythematosus Patients: Preliminary Data " Int. Arc. Allergy and Immunology , vol. 100, 1993, pp. 215-218.

 

-----------------

Fishman, P.; Bakimer, R.; Blank, M.; Sredni-Kenigsbuch, D.; Djaldetti, M. and Shoenfeld, Y. "The Putative Role of Cytokines in the Induction of Primary Anti-Phospholipid Syndrome in Mice" Clin. Exp. Imm., vol. 90, 1992, pp. 266-270.

 

-----------------

Fishman, P.; Shoenfeld, Y.; Hart, J.; Zigelman, R.; Shamir, Y.; Feldberg, D.; Inbar, O.; Sredni-Kenigsbuch, D. and Djaldetti, M. "Interleukine-3-Like Activity Levels in Pregnant Women: Possible Modulation by Progresteron " J. Rep. Immunol. , vol. 22, 1992, pp. 211-216.

 

-----------------

Lenz, A.; Alter, A.; Radnay, J.; Goldman, J.; Sredni-Kenigsbuch, D. and Rozensajn, L.A. "Stimulation of Human T Cell Colony Growth by Lymphocyte Colony Enhancing Factor Derived from Lymphocyte Subpopulations " Nat. Immun. Cell Growth Regul. , vol. 9, 1990, pp. 228-236.

 

-----------------

Barda-Saad, M.; Sredni-Kenigsbuch, D.; Zemer, R.; Lentz, R. and Rozensajn, L.A. "T Lymphocyte colony enhancing factor" Harefuah , vol. 118, 1990, pp. 92-95.

 

-----------------

Rozensajn, L.A.; Goldman, J.; Alter, A.; Radnay, J.; Sredni-Kenigsbuch, D.; Zemer, R. and Lenz, R. "tT Lymphocyte Colony Stimulating Factor, LCEF, a Non Species Specific Factor Generated by Human Blood Mononuclear Cells and Murine Thymocytes " Exp. Hemat. , vol. 17, 1989, pp. 441.

 

-----------------

Sredni, B.; Shrem, E.; Sredni-Kenigsbuch, D. and Fogel, A. "Interleukin-2 Production in Human-Lymphocyte Cultures After Infection with Rubella-Virus" Isr. J. Med. Sci., vol. 21, 1985, pp. 182.

 

-----------------

Sredni-Kenigsbuch, D. and Grossman, S. "Hydroperoxide Isomers and Keto Hydroxy Product from Oxidation of Linoleic Acid by Eggplant Lypoxigenase " Phytochemistry , vol. 19, 1980, pp. 1335-1337.
 

Research

The Involvement of various growth factors in various diseases